Publications

Ral GTPases promote breast cancer metastasis by controlling biogenesis and organ targeting of exosomes.

Ghoroghi S, Mary B, Larnicol A, Asokan N, Klein A, Osmani N, Busnelli I, Delalande F, Paul N, Halary S, Gros F, Fouillen L, Haeberle AM, Royer C, Spiegelhalter C, André-Grégoire G, Mittelheisser V, Detappe A, Murphy K, Timpson P, Carapito R, Blot-Chabaud M, Gavard J, Carapito C, Vitale N, Lefebvre O, Goetz JG, Hyenne V

Elife 2021; 10():

Relative Adipose Tissue Failure in Alström Syndrome Drives Obesity-Induced Insulin Resistance.

Geberhiwot T, Baig S, Obringer C, Girard D, Dawson C, Manolopoulos K, Messaddeq N, Bel Lassen P, Clement K, Tomlinson JW, Steeds RP, Dollfus H, Petrovsky N, Marion V

Diabetes 2021; 70(2):364-376

Tunable functionalization of nano-emulsions using amphiphilic polymers.

Rehman AU, Anton N, Bou S, Schild J, Messaddeq N, Vandamme T, Akram S, Klymchenko A, Collot M

Soft Matter 2021; 17(7):1788-1795

Pickering nano-emulsions stabilized by Eudragit RL100 nanoparticles as oral drug delivery system for poorly soluble drugs.

Dieng SM, Omran Z, Anton N, Thioune O, Djiboune AR, Sy PM, Messaddeq N, Ennahar S, Diarra M, Vandamme T

Colloids Surf B Biointerfaces 2020; 191():111010

Amphiphysin 2 modulation rescues myotubular myopathy and prevents focal adhesion defects in mice.

Lionello VM(1)(2)(3)(4), Nicot AS(1)(2)(3)(4)(5)(6), Sartori M(1)(2)(3)(4), Kretz C(1)(2)(3)(4), Kessler P(1)(2)(3)(4), Buono S(1)(2)(3)(4), Djerroud S(1)(2)(3)(4), Messaddeq N(1)(2)(3)(4), Koebel P(1)(2)(3)(4), Prokic I(1)(2)(3)(4), Herault Y(1)(2)(3)(4), Romero NB(7)(8)(9), Laporte J(10)(2)(3)(4), Cowling BS(1)(2)(3)(4).

Sci Transl Med 2019; 11(484):eaav1866

In vivo phenotypic and molecular characterization of retinal degeneration in mouse models of three ciliopathies.

Brun A(1), Yu X(1), Obringer C(1), Ajoy D(1), Haser E(1), Stoetzel C(1), Roux MJ(2), Messaddeq N(2), Dollfus H(1), Marion V(3).

Exp Eye Res 2019; 186():107721

Macrophage functionality and homeostasis in response to oligoethyleneglycol-coated IONPs: Impact of a dendritic architecture.

Casset A(1), Jouhannaud J(2), Garofalo A(2), Spiegelhalter C(3), Nguyen DV(2), Felder-Flesch D(2), Pourroy G(2), Pons F(4).

Int J Pharm 2019; 556():287-300

Magnetite- and Iodine-Containing Nanoemulsion as a Dual Modal Contrast Agent for X-ray/Magnetic Resonance Imaging.

Wallyn J(1), Anton N(1), Mertz D(2), Begin-Colin S(2), Perton F(2), Serra CA(3), Franconi F(4)(5), Lemaire L(4)(5), Chiper M(6), Libouban H(7), Messaddeq N(8), Anton H(9), Vandamme TF(1).

ACS Appl Mater Interfaces 2019; 11(1):403-416

STIM1 over-activation generates a multi-systemic phenotype affecting skeletal muscle, spleen, eye, skin, bones, and the immune system in mice.

Silva-Rojas R(1), Treves S(2), Jacobs H(1)(3), Kessler P(1), Messaddeq N(1), Laporte J(1), Bohm J(1).

Hum Mol Genet 2019; 28(10):1579-1593

Toward the Formulation of Stable Micro and Nano Double Emulsions through a Silica Coating on Internal Water Droplets.

Akram S, Wang X, Vandamme TF, Collot M, Rehman AU, Messaddeq N, Mely Y, Anton N.

Langmuir 2019; 35(6):2313-2325

Transmission Microsphere-Assisted Dark-Field Microscopy

Perrin, S (Perrin, Stephane)[ 1 ] ; Li, HY (Li, Hongyu)[ 1 ] ; Badu, K (Badu, Keshia)[ 1 ] ; Comparon, T (Comparon, Thomas)[ 1 ] ; Quaranta, G (Quaranta, Giorgio)[ 2,3 ] ; Messaddeq, N (Messaddeq, Nadia)[ 4 ] ; Lemercier, N (Lemercier, Nicolas)[ 4 ] ; Montgomery, P (Montgomery, Paul)[ 1 ] ; Vonesch, JL (Vonesch, Jean-Luc)[ 4 ] ; Lecler, S (Lecler, Sylvain)[ 1 ]

PHYSICA STATUS SOLIDI-RAPID RESEARCH LETTERS 2019; 13(2):1800445

3DClusterViSu: 3D clustering analysis of super-resolution microscopy data by 3D Voronoi tessellations.

Andronov L(1)(2)(3)(4), Michalon J(1)(2)(3)(4), Ouararhni K(1)(2)(3)(4), Orlov I(1)(2)(3)(4), Hamiche A(1)(2)(3)(4), Vonesch JL(1)(2)(3)(4), Klaholz BP(1)(2)(3)(4).

Bioinformatics 2018; 34(17):3004-3012

Abnormal lipid storage related to adipocyte shrinkage in acquired partial lipodystrophy (Barraquer-Simons syndrome).

Velter C(1), Messaddeq N(2), Levy E(1), Morruzzi C(1), Cribier B(1), Dali-Youcef N(2)(3), Lipsker D(1).

J Eur Acad Dermatol Venereol 2018; (0):0

A new formulation of poly(MAOTIB) nanoparticles as an efficient contrast agent for in vivo X-ray imaging.

Wallyn J(1), Anton N(2), Serra CA(3), Bouquey M(3), Collot M(4), Anton H(4), Weickert JL(5), Messaddeq N(5), Vandamme TF(1).

Acta Biomater 2018; 66():200-212

Microfluidic-Assisted Production of Size-Controlled Superparamagnetic Iron Oxide Nanoparticles-Loaded Poly(methyl methacrylate) Nanohybrids.

Ding S(1)(2), Attia MF(3)(4)(5), Wallyn J(3), Taddei C(1)(6), Serra CA(1), Anton N(3), Kassem M(7), Schmutz M(1), Er-Rafik M(1), Messaddeq N(8), Collard A(1), Yu W(1), Giordano M(6), Vandamme TF(3).

Langmuir 2018; 34(5):1981-1991

Modulation of large dense core vesicle insulin content mediates rhythmic hormone release from pancreatic beta cells over the 24h cycle.

Quinault A(1), Leloup C(1), Denwood G(2), Spiegelhalter C(3), Rodriguez M(4), Lefebvre P(5), Messaddeq N(3), Zhang Q(2), Dacquet C(6), Penicaud L(1), Collins SC(1)(3).

PLoS One 2018; 13(3):e0193882

Phagocytosis by Sertoli Cells: Analysis of Main Phagocytosis Steps by Confocal and Electron Microscopy.

Yefimova MG(1)(2), Messaddeq N(3)(4)(5)(6), Meunier AC(1), Cantereau A(1)(7), Jegou B(8), Bourmeyster N(9)(10).

Methods Mol Biol 2018; 1748():85-101

Pickering nano-emulsion as a nanocarrier for pH-triggered drug release.

Sy PM(1), Anton N(2), Idoux-Gillet Y(3), Dieng SM(1), Messaddeq N(4), Ennahar S(5), Diarra M(6), Vandamme TF(7).

Int J Pharm 2018; 549(1-2):299-305

ReAsH/tetracystein-based Correlative Light-Electron Microscopy for HIV-1 imaging during the early stages of infection.

Lysova I(1), Spiegelhalter C(2), Real E(1), Zgheib S(1), Anton H(1), Mely Y(3).

Methods Appl Fluoresc 2018; 6(4):045001

Single Intramuscular Injection of AAV-shRNA Reduces DNM2 and Prevents Myotubular Myopathy in Mice.

Tasfaout H(1), Lionello VM(1), Kretz C(1), Koebel P(2), Messaddeq N(3), Bitz D(4), Laporte J(5), Cowling BS(6).

Mol Ther 2018; 26(4):1082-1092

Study of the chorion of seasonal and non-seasonal Africa and Neotropical oviparous Cyprinodontiforme fishes

Messaddeq, N, Hergueux, J, Weickert, JL, Romand, R

Environmental Biology of Fishes 2018; 101(2):287-299

The MTM1-UBQLN2-HSP complex mediates degradation of misfolded intermediate filaments in skeletal muscle.

Gavriilidis C(1)(2)(3)(4), Laredj L(1)(2)(3)(4), Solinhac R(5), Messaddeq N(2)(3)(4), Viaud J(5), Laporte J(1)(2)(3)(4), Sumara I(2)(3)(4)(6), Hnia K(7)(8)(9)(10)(11).

Nat Cell Biol 2018; 20(2):198-210

Microtome-integrated microscope system for high sensitivity tracking of in-resin fluorescence in blocks and ultrathin sections for correlative microscopy.

Lemercier N(1)(2)(3)(4), Middel V(5), Hentsch D(1)(2)(3)(4), Taubert S(1)(2)(3)(4), Takamiya M(5), Beil T(5), Vonesch JL(1)(2)(3)(4), Baumbach T(6), Schultz P(7)(8)(9)(10), Antony C(1)(2)(3)(4)(5), Strahle U(11).

Sci Rep 2017; 7(1):13583

Organ size control via hydraulically gated oscillations.

Ruiz-Herrero T(1), Alessandri K(2)(3), Gurchenkov BV(4)(5)(6)(7), Nassoy P(2)(3), Mahadevan L(8)(9).

Development 2017; 144(23):4422-4427

The histone code reader Spin1 controls skeletal muscle development.

Greschik H(1), Duteil D(1), Messaddeq N(2), Willmann D(1), Arrigoni L(3), Sum M(1), Jung M(4)(5), Metzger D(2), Manke T(3), Gunther T(1), Schule R(1)(5)(6).

Cell Death Dis 2017; 8(11):e3173

Transcription Factor CTIP1/ BCL11A Regulates Epidermal Differentiation and Lipid Metabolism During Skin Development.

Li S(1), Teegarden A(2), Bauer EM(1), Choi J(3), Messaddeq N(4), Hendrix DA(2), Ganguli-Indra G(1)(5), Leid M(1)(2)(5)(6), Indra AK(7)(8)(9)(10)(11).

Sci Rep 2017; 7(1):13427

A 3D printed microfluidic device for production of functionalized hydrogel microcapsules for culture and differentiation of human Neuronal Stem Cells (hNSC).

Alessandri K(1), Feyeux M(2), Gurchenkov B(3), Delgado C(2), Trushko A(4), Krause KH(2), Vignjevi? D(5), Nassoy P(6), Roux A(7).

Lab Chip 2016; 16(9):1593-604

A Theranostic Agent Combining a Two-Photon-Absorbing Photosensitizer for Photodynamic Therapy and a Gadolinium(III) Complex for MRI Detection.

Schmitt J(1), Heitz V(2), Sour A(1), Bolze F(3), Kessler P(4), Flamigni L(5), Ventura B(6), Bonnet CS(7), Tóth É(8).

Chemistry 2016; 22(8):2775-86

Corrigendum: Matrix metalloproteinase 11 protects from diabesity and promotes metabolic switch.

Dali-Youcef N, Hnia K, Blaise S, Messaddeq N, Blanc S, Postic C, Valet P, Tomasetto C, Rio MC.

Sci Rep 2016; 6():26916

Impact of chronic morphine on delta opioid receptor-expressing neurons in the mouse hippocampus.

Erbs E(1), Faget L(1), Ceredig RA(2), Matifas A(1), Vonesch JL(3), Kieffer BL(4), Massotte D(5).

Neuroscience 2016; 313():46-56

In vivo imaging of skeletal muscle in mice highlights muscle defects in a model of myotubular myopathy.

Mercier L(1), Bohm J(2), Fekonja N(3), Allio G(3), Lutz Y(4), Koch M(4), Goetz JG(3), Laporte J(2).

Intravital 2016; 5(1):e1168553

Lsd1 Ablation Triggers Metabolic Reprogramming of Brown Adipose Tissue.

Duteil D(1), Tosic M(1), Lausecker F(1), Nenseth HZ(1), Müller JM(1), Urban S(1), Willmann D(1), Petroll K(2), Messaddeq N(3), Arrigoni L(4), Manke T(4), Kornfeld JW(5), Brüning JC(5), Zagoriy V(6), Meret M(6), Dengjel J(7), Kanouni T(8), Schüle R(9).

Cell Rep 2016; 17(4):1008-1021

Myelinosomes act as natural secretory organelles in Sertoli cells to prevent accumulation of aggregate-prone mutant Huntingtin and CFTR.

Yefimova MG(1,)(2), Bere E(3), Cantereau-Becq A(1,)(3), Harnois T(1), Meunier AC(1), Messaddeq N(4,)(5,)(6,)(7), Becq F(1), Trottier Y(4,)(5,)(6,)(7), Bourmeyster N(8,)(9).

Hum Mol Genet 2016; 25(19):4170-4185

One-step synthesis of iron oxide polypyrrole nanoparticles encapsulating ketoprofen as model of hydrophobic drug.

Attia MF(1), Anton N(2), Khan IU(3), Serra CA(4), Messaddeq N(5), Jakhmola A(6), Vecchione R(6), Vandamme T(7).

Int J Pharm 2016; 508(1-2):61-70

Prokineticin receptor 1 is required for mesenchymal-epithelial transition in kidney development.

Arora H(1), Boulberdaa M(1), Qureshi R(1), Bitirim V(1), Messadeq N(2), Dolle P(2), Nebigil CG(3).

FASEB J 2016; 30(8):2733-2740

Prokineticin receptor-1 signaling promotes Epicardial to Mesenchymal Transition during heart development.

Arora H(1), Boulberdaa M(1), Qureshi R(1), Bitirim V(1), Gasser A(1), Messaddeq N(2), Dolle P(2), Nebigil CG(1).

Sci Rep 2016; 6():25541

SharpViSu: integrated analysis and segmentation of super-resolution microscopy data.

Andronov L(1), Lutz Y(1), Vonesch JL(1), Klaholz BP(1).

Bioinformatics 2016; 32(14):2239-41

Three-dimensional Micro-culture System for Tooth Tissue Engineering.

Kuchler-Bopp S(1), Bécavin T(2), Kökten T(3), Weickert JL(4), Keller L(5), Lesot H(5), Deveaux E(6), Benkirane-Jessel N(5).

J Dent Res 2016; 95(6):657-664

Trafficking of Endogenous Immunoglobulins by Endothelial Cells at the Blood-Brain Barrier.

Villaseñor R(1), Ozmen L(1), Messaddeq N(2), Grüninger F(1), Loetscher H(1), Keller A(3), Betsholtz C(4,)(5), Freskgård PO(1), Collin L(1).

Sci Rep 2016; 6():25658

Well-organized spheroids as a new platform to examine cell interaction and behaviour during organ development.

Becavin T(1,)(2), Kuchler-Bopp S(3,)(4), Kokten T(1,)(5,)(6), Huck O(1,)(5), Messaddeq N(7), Lesot H(1,)(5), Deveaux E(2), Benkirane-Jessel N(1,)(5), Laetitia K(1,)(5).

Cell Tissue Res 2016; 366(3):601-615

A mu-delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks.

Erbs E(1), Faget L, Scherrer G, Matifas A, Filliol D, Vonesch JL, Koch M, Kessler P, Hentsch D, Birling MC, Koutsourakis M, Vasseur L, Veinante P, Kieffer BL, Massotte D.

Brain Struct Funct 2015; 220(2):677-702

A novel function of Huntingtin in the cilium and retinal ciliopathy in Huntington's disease mice.

Karam A(1), Tebbe L(2), Weber C(1), Messaddeq N(1), Morlé L(3), Kessler P(1), Wolfrum U(4), Trottier Y(5).

Neurobiol Dis 2015; 80():15-28

Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.

Dubos A(1), Castells-Nobau A(2), Meziane H(3), Oortveld MA(2), Houbaert X(4), Iacono G(5), Martin C(4), Mittelhaeuser C(3), Lalanne V(3), Kramer JM(2), Bhukel A(6), Quentin C(7), Slabbert J(8), Verstreken P(8), Sigrist SJ(7), Messaddeq N(9), Birling MC(3), Selloum M(3), Stunnenberg HG(5), Humeau Y(4), Schenck A(10), Herault Y(11).

Hum Mol Genet 2015; 24(23):6736-55

Developmental Alterations in Heart Biomechanics and Skeletal Muscle Function in Desmin Mutants Suggest an Early Pathological Root for Desminopathies.

Ramspacher C(1), Steed E(1), Boselli F(1), Ferreira R(1), Faggianelli N(1), Roth S(1), Spiegelhalter C(1), Messaddeq N(1), Trinh L(2), Liebling M(3), Chacko N(3), Tessadori F(4), Bakkers J(4), Laporte J(1), Hnia K(1), Vermot J(5).

Cell Rep 2015; 11(10):1564-76

Functionalization of nano-emulsions with an amino-silica shell at the oil–water interface

Mohamed F. Attia,abc Nicolas Anton,*ab Redouane Bouchaala,ade Pascal Didier,ad Youri Arntz,ad Nadia Messaddeq,f Andrey S. Klymchenko,ad Yves Mely ´ ad and Thierry F. Vandammeab

RSC Advances The Royal Society of Chemistry 2015; 5():74353-74361

Insulin granules. Insulin secretory granules control autophagy in pancreatic beta cells.

Goginashvili A, Zhang Z, Erbs E, Spiegelhalter C, Kessler P, Mihlan M, Pasquier A, Krupina K, Schieber N, Cinque L, Morvan J, Sumara I, Schwab Y, Settembre C, Ricci R.

Science 2015; 347(6224):878-82

Integrated annotation and analysis of in situ hybridization images using the ImAnno system: application to the ear and sensory organs of the fetal mouse.

Romand R(1), Ripp R(2), Poidevin L(3), Boeglin M(4), Geffers L(5), Dollé P(1), Poch O(3).

PLoS One 2015; 10(2):e0118024

Microfluidic conceived Trojan microcarriers for oral delivery of nanoparticles.

Khan IU(1), Serra CA(2), Anton N(3), Er-Rafik M(4), Blanck C(4), Schmutz M(4), Kraus I(5), Messaddeq N(6), Sutter C(7), Anton H(8), Klymchenko AS(8), Vandamme TF(3).

Int J Pharm 2015; 493(1-2):7-15

Mutations in the latent TGF-beta binding protein 3 (LTBP3) gene cause brachyolmia with amelogenesis imperfecta.

Huckert M(1), Stoetzel C(2), Morkmued S(3), Laugel-Haushalter V(4), Geoffroy V(2), Muller J(5), Clauss F(6), Prasad MK(2), Obry F(7), Raymond JL(8), Switala M(7), Alembik Y(9), Soskin S(10), Mathieu E(11), Hemmerlé J(11), Weickert JL(4), Dabovic BB(12), Rifkin DB(12), Dheedene A(13), Boudin E(14), Caluseriu O(15), Cholette MC(15), Mcleod R(15), Antequera R(16), Gellé MP(17), Coeuriot JL(18), Jacquelin LF(18), Bailleul-Forestier I(19), Manière MC(7), Van Hul W(14), Bertola D(20), Dollé P(4), Verloes A(21), Mortier G(22), Dollfus H(23), Bloch-Zupan A(24).

Hum Mol Genet 2015; 24(11):3038-49

Opposite phenotypes of muscle strength and locomotor function in mouse models of partial trisomy and monosomy 21 for the proximal Hspa13-App region.

Brault V(1), Duchon A(1), Romestaing C(2), Sahun I(3), Pothion S(4), Karout M(1), Borel C(5), Dembele D(1), Bizot JC(6), Messaddeq N(1), Sharp AJ(7), Roussel D(2), Antonarakis SE(8), Dierssen M(3), Herault Y(9).

PLoS Genet 2015; 11(3):e1005062

RAL-1 controls multivesicular body biogenesis and exosome secretion.

Hyenne V(1), Apaydin A(2), Rodriguez D(2), Spiegelhalter C(3), Hoff-Yoessle S(2), Diem M(2), Tak S(2), Lefebvre O(4), Schwab Y(5), Goetz JG(4), Labouesse M(6).

J Cell Biol 2015; 211(1):27-37

The Src Homology and Collagen A (ShcA) Adaptor Protein Is Required for the Spatial Organization of the Costamere/Z-disk Network during Heart Development.

Mlih M(1), Host L(1), Martin S(1), Niederhoffer N(2), Monassier L(2), Terrand J(1), Messaddeq N(3), Radke M(4), Gotthardt M(4), Bruban V(1), Kober F(5), Bernard M(5), Canet-Soulas E(6), Abt-Jijon F(1), Boucher P(7), Matz RL(8).

J Biol Chem 2015; 290(4):2419-30

The transcriptional coregulator PGC-1beta controls mitochondrial function and anti-oxidant defence in skeletal muscles.

Gali Ramamoorthy T(1), Laverny G(1), Schlagowski AI(2), Zoll J(2), Messaddeq N(1), Bornert JM(1), Panza S(1,)(3), Ferry A(4), Geny B(2), Metzger D(1).

Nat Commun 2015; 6():10210

Autistic-like syndrome in mu opioid receptor null mice is relieved by facilitated mGluR4 activity.

Becker JA(1), Clesse D(2), Spiegelhalter C(3), Schwab Y(3), Le Merrer J(1), Kieffer BL(1).

Neuropsychopharmacology 2014; 39(9):2049-60

Biodistribution of X-ray iodinated contrast agent in nano-emulsions is controlled by the chemical nature of the oily core.

Attia MF(1), Anton N, Chiper M, Akasov R, Anton H, Messaddeq N, Fournel S, Klymchenko AS, Mély Y, Vandamme TF.

ACS Nano 2014; 8(10):10537-50

Correlative light and electron microscopy: from live cell dynamic to 3D ultrastructure.

Spiegelhalter C(1), Laporte JF, Schwab Y.

Methods Mol Biol: Electron Microscopy 2014; 1117():485-501

Higher chromatin mobility supports totipotency and precedes pluripotency in vivo.

Boskovic A(1), Eid A(1), Pontabry J(1), Ishiuchi T(1), Spiegelhalter C(1), Raghu Ram EV(2), Meshorer E(2), Torres-Padilla ME(1).

Genes Dev 2014; 28(10):1042-7

Immunomodulation stimulates the innervation of engineered tooth organ.

Kökten T(1), Bécavin T(2), Keller L(2), Weickert JL(3), Kuchler-Bopp S(1), Lesot H(1).

PLoS One 2014; 9(1):e86011

Microfluidic conceived drug loaded Janus particles in side-by-side capillaries device.

Khan IU(1), Serra CA(2), Anton N(3), Li X(3), Akasov R(4), Messaddeq N(5), Kraus I(6), Vandamme TF(3).

Int J Pharm 2014; 473(1-2):239-49

Nanofibers implant functionalized by neural growth factor as a strategy to innervate a bioengineered tooth.

Eap S(1), Bécavin T, Keller L, Kökten T, Fioretti F, Weickert JL, Deveaux E, Benkirane-Jessel N, Kuchler-Bopp S.

Adv Healthc Mater 2014; 3(3):386-91

Nuclear position dictates DNA repair pathway choice.

Lemaître C(1), Grabarz A(1), Tsouroula K(1), Andronov L(1), Furst A(1), Pankotai T(1), Heyer V(1), Rogier M(1), Attwood KM(2), Kessler P(1), Dellaire G(2), Klaholz B(1), Reina-San-Martin B(1), Soutoglou E(1).

Genes Dev 2014; 28(22):2450-63

Poly--caprolactone tungsten oxide nanoparticles as a contrast agent for X-ray computed tomography.

Jakhmola A(1), Anton N(2), Anton H(3), Messaddeq N(4), Hallouard F(5), Klymchenko A(3), Mely Y(3), Vandamme TF(1).

Biomaterials 2014; 35(9):2981-6

Prevention and reversal of severe mitochondrial cardiomyopathy by gene therapy in a mouse model of Friedreich's ataxia.

Perdomini M(1), Belbellaa B(1), Monassier L(2), Reutenauer L(3), Messaddeq N(3), Cartier N(4), Crystal RG(5), Aubourg P(6), Puccio H(3).

Nat Med 2014; 20(5):542-7

A chimerical phagocytosis model reveals the recruitment by Sertoli cells of autophagy for the degradation of ingested illegitimate substrates.

Yefimova MG(1), Messaddeq N, Harnois T, Meunier AC, Clarhaut J, Noblanc A, Weickert JL, Cantereau A, Philippe M, Bourmeyster N, Benzakour O.

Autophagy 2013; 9(5):653-66

An integrated diagnosis strategy for congenital myopathies.

Böhm J, Vasli N, Malfatti E, Le Gras S, Feger C, Jost B, Monnier N, Brocard J, Karasoy H, Gérard M, Walter MC, Reilich P, Biancalana V, Kretz C, Messaddeq N, Marty I, Lunardi J, Romero NB, Laporte J.

PLoS One 2013; 8(6):e67527

Birbeck granule-like "organized smooth endoplasmic reticulum" resulting from the expression of a cytoplasmic YFP-tagged langerin.

Lenormand C(1), Spiegelhalter C, Cinquin B, Bardin S, Bausinger H, Angénieux C, Eckly A, Proamer F, Wall D, Lich B, Tourne S, Hanau D, Schwab Y, Salamero J, de la Salle H.

PLoS One 2013; 8(4):e60813

Constitutive activation of the calcium sensor STIM1 causes tubular-aggregate myopathy.

Böhm J(1), Chevessier F, Maues De Paula A, Koch C, Attarian S, Feger C, Hantaï D, Laforêt P, Ghorab K, Vallat JM, Fardeau M, Figarella-Branger D, Pouget J, Romero NB, Koch M, Ebel C, Levy N, Krahn M, Eymard B, Bartoli M, Laporte J.

Am J Hum Genet 2013; 92(2):271-8

Dynamin 2 homozygous mutation in humans with a lethal congenital syndrome.

Koutsopoulos OS, Kretz C, Weller CM, Roux A, Mojzisova H, Böhm J, Koch C, Toussaint A, Heckel E, Stemkens D, Ter Horst SA, Thibault C, Koch M, Mehdi SQ, Bijlsma EK, Mandel JL, Vermot J, Laporte J.

Eur J Hum Genet 2013; 21(6):637-42

Dynein mutations associated with hereditary motor neuropathies impair mitochondrial morphology and function with age.

Eschbach J, Sinniger J, Bouitbir J, Fergani A, Schlagowski AI, Zoll J, Geny B, René F, Larmet Y, Marion V, Baloh RH, Harms MB, Shy ME, Messadeq N, Weydt P, Loeffler JP, Ludolph AC, Dupuis L.

Neurobiol Dis 2013; 58():220-30

Immunomodulatory properties of multi-walled carbon nanotubes in peripheral blood mononuclear cells from healthy subjects and allergic patients.

Laverny G, Casset A, Purohit A, Schaeffer E, Spiegelhalter C, de Blay F, Pons F.

Toxicol Lett 2013; 217(2):91-101

Iodinated -tocopherol nano-emulsions as non-toxic contrast agents for preclinical X-ray imaging.

Li X, Anton N, Zuber G, Zhao M, Messaddeq N, Hallouard F, Fessi H, Vandamme TF.

Biomaterials 2013; 34(2):481-91

Lack of myotubularin (MTM1) leads to muscle hypotrophy through unbalanced regulation of the autophagy and ubiquitin-proteasome pathways.

Al-Qusairi L, Prokic I, Amoasii L, Kretz C, Messaddeq N, Mandel JL, Laporte J.

FASEB J 2013; 27(8):3384-94

Neurons and cardiomyocytes derived from induced pluripotent stem cells as a model for mitochondrial defects in Friedreich's ataxia.

Hick A, Wattenhofer-Donzé M, Chintawar S, Tropel P, Simard JP, Vaucamps N, Gall D, Lambot L, André C, Reutenauer L, Rai M, Teletin M, Messaddeq N, Schiffmann SN, Viville S, Pearson CE, Pandolfo M, Puccio H.

Dis Model Mech 2013; 6(3):608-21

Prokineticin receptor-1 is a new regulator of endothelial insulin uptake and capillary formation to control insulin sensitivity and cardiovascular and kidney functions.

Dormishian M(1), Turkeri G, Urayama K, Nguyen TL, Boulberdaa M, Messaddeq N, Renault G, Henrion D, Nebigil CG.

J Am Heart Assoc 2013; 2(5):e000411

Retinoic acid deficiency impairs the vestibular function.

Romand R, Krezel W, Beraneck M, Cammas L, Fraulob V, Messaddeq N, Kessler P, Hashino E, Dollé P.

J Neurosci 2013; 33(13):5856-66

Site-specific Mtm1 mutagenesis by an AAV-Cre vector reveals that myotubularin is essential in adult muscle.

Joubert R, Vignaud A, Le M, Moal C, Messaddeq N, Buj-Bello A.

Hum Mol Genet 2013; 22(9):1856-66

STARD3 or STARD3NL and VAP form a novel molecular tether between late endosomes and the ER.

Alpy F(1), Rousseau A, Schwab Y, Legueux F, Stoll I, Wendling C, Spiegelhalter C, Kessler P, Mathelin C, Rio MC, Levine TP, Tomasetto C.

J Cell Sci 2013; 126(Pt 23):5500-5512

Straightforward selection of broadly neutralizing single-domain antibodies targeting the conserved CD4 and coreceptor binding sites of HIV-1 gp120.

Matz J, Kessler P, Bouchet J, Combes O, Ramos OH, Barin F, Baty D, Martin L, Benichou S, Chames P.

J Virol 2013; 87(2):1137-49

BBS-induced ciliary defect enhances adipogenesis, causing paradoxical higher-insulin sensitivity, glucose usage, and decreased inflammatory response.

Marion V, Mockel A, De Melo C, Obringer C, Claussmann A, Simon A, Messaddeq N, Durand M, Dupuis L, Loeffler JP, King P, Mutter-Schmidt C, Petrovsky N, Stoetzel C, Dollfus H.

Cell Metab 2012; 16(3):363-77

Clinical data and characterization of the liver conditional mouse model exclude neoplasia as a non-neurological manifestation associated with Friedreich's ataxia.

Martelli A, Friedman LS, Reutenauer L, Messaddeq N, Perlman SL, Lynch DR, Fedosov K, Schulz JB, Pandolfo M, Puccio H.

Dis Model Mech 2012; 5(6):860-869

Distribution of delta opioid receptor-expressing neurons in the mouse hippocampus.

Erbs E, Faget L, Scherrer G, Kessler P, Hentsch D, Vonesch JL, Matifas A, Kieffer BL, Massotte D.

Neuroscience 2012; 221():203-13

Elicitation of neutralizing antibodies directed against CD4-induced epitope(s) using a CD4 mimetic cross-linked to a HIV-1 envelope glycoprotein.

Dey AK, Burke B, Sun Y, Sirokman K, Nandi A, Hartog K, Lian Y, Geonnotti AR, Montefiori D, Franti M, Martin G, Carfi A, Kessler P, Martin L, Srivastava IK, Barnett SW.

PLoS One 2012; 7(1):e30233

Expression of exocytosis proteins in rat supraoptic nucleus neurons.

Tobin V, Schwab Y, Lelos N, Onaka T, Pittman Q, Ludwig M.

J Neuroendocrinol 2012; 24(4):629-641

Human prion protein binds Argonaute and promotes accumulation of microRNA effector complexes.

Gibbings D, Leblanc P, Jay F, Pontier D, Michel F, Schwab Y, Alais S, Lagrange T, Voinnet O.

Nat Struct Mol Biol 2012; 19(5):517-24

In Vivo Evidence That TRAF4 Is Required for Central Nervous System Myelin Homeostasis.

Blaise S, Kneib M, Rousseau A, Gambino F, Chenard MP, Messadeq N, Muckenstrum M, Alpy F, Tomasetto C, Humeau Y, Rio MC.

PLoS One 2012; 7(2):e30917

In vivo visualization of delta opioid receptors upon physiological activation uncovers a distinct internalization profile.

Faget L, Erbs E, Le Merrer J, Scherrer G, Matifas A, Benturquia N, Noble F, Decossas M, Koch M, Kessler P, Vonesch JL, Schwab Y, Kieffer BL, Massotte D.

J Neurosci 2012; 32(21):7301-10

Lung deposition and toxicological responses evoked by multi-walled carbon nanotubes dispersed in a synthetic lung surfactant in the mouse

Ronzani C., Spiegelhalter C., Vonesch J.L., Lebeau L., Pons F.

Arch Toxicol 2012; 86(1):137-49

MiniCD4 microbicide prevents HIV infection of human mucosal explants and vaginal transmission of SHIV(162P3) in cynomolgus macaques.

Dereuddre-Bosquet N, Morellato-Castillo L, Brouwers J, Augustijns P, Bouchemal K, Ponchel G, Ramos OH, Herrera C, Stefanidou M, Shattock R, Heyndrickx L, Vanham G, Kessler P, Le Grand R, Martin L.

PLoS Pathog 2012; 8(12):e1003071

MiniCD4 protein resistance mutations affect binding to the HIV-1 gp120 CD4 binding site and decrease entry efficiency.

Grupping K, Selhorst P, Michiels J, Vereecken K, Heyndrickx L, Kessler P, Vanham G, Martin L, Ariën KK.

Retrovirology 2012; 9():36

Myotubular myopathy and the neuromuscular junction: a novel therapeutic approach from mouse models.

Dowling JJ, Joubert R, Low SE, Durban AN, Messaddeq N, Li X, Dulin-Smith AN, Snyder AD, Marshall ML, Marshall JT, Beggs AH, Buj-Bello A, Pierson CR.

Dis Model Mech 2012; 5(6):852-9

Perispeckles are major assembly sites for the exon junction core complex.

Daguenet E(1), Baguet A, Degot S, Schmidt U, Alpy F, Wendling C, Spiegelhalter C, Kessler P, Rio MC, Le Hir H, Bertrand E, Tomasetto C.

Mol Biol Cell 2012; 23(9):1765-82

Primary T-tubule and autophagy defects in the phosphoinositide phosphatase Jumpy/MTMR14 knockout mice muscle.

Hnia K(1), Kretz C, Amoasii L, Böhm J, Liu X, Messaddeq N, Qu CK, Laporte J.

Adv Biol Regul 2012; 52(1):98-107

Selective autophagy degrades DICER and AGO2 and regulates miRNA activity.

Gibbings D(1), Mostowy S, Jay F, Schwab Y, Cossart P, Voinnet O.

Nat Cell Biol 2012; 14(12):1314-21

Unlike for human monocytes after LPS activation, release of TNF- by THP-1 cells is produced by a TACE catalytically different from constitutive TACE.

Moreira-Tabaka H, Peluso J, Vonesch JL, Hentsch D, Kessler P, Reimund JM, Dumont S, Muller CD.

PLoS One 2012; 7(3):e34184

Vezatin is essential for dendritic spine morphogenesis and functional synaptic maturation.

Danglot L(1), Freret T, Le Roux N, Narboux Nême N, Burgo A, Hyenne V, Roumier A, Contremoulins V, Dauphin F, Bizot JC, Vodjdani G, Gaspar P, Boulouard M, Poncer JC, Galli T, Simmler MC.

J Neurosci 2012; 32(26):9007-22

4 decisions that can affect your anesthesia subsidy.

Koch M, Calder DB.

Healthc Financ Manage 2011; 65(4):104-8

A tension-induced mechanotransduction pathway promotes epithelial morphogenesis

Zhang H., Landmann F., Zahreddine H., Rodriguez D., Koch M., Labouesse M.

Nature 2011; 471(7336):99-103

Cell death after high-LET irradiation in orthotopic human hepatocellular carcinoma in vivo

Altmeyer A., Ignat M., Denis J.M., Messaddeq N., Gueulette J., Mutter D., Bischoff P.

In Vivo 2011; 25(1):1-9

Conditional ablation of integrin alpha-6 in mouse epidermis leads to skin fragility and inflammation

Niculescu C., Ganguli-Indra G., Pfister V., Dupe V., Messaddeq N., De Arcangelis A., Georges-Labouesse E.

Eur J Cell Biol 2011; 90(2-3):270-7

Deciphering correct strategies for multiprotein complex assembly by co-expression: Application to complexes as large as the histone octamer

Diebold M.L., Fribourg S., Koch M., Metzger T., Romier C.

J Struct Biol 2011; 175(2):178-88

Defects in amphiphysin 2 (BIN1) and triads in several forms of centronuclear myopathies

Toussaint A., Cowling B.S., Hnia K., Mohr M., Oldfors A., Schwab Y., Yis U., Maisonobe T., Stojkovic T., Wallgren-Pettersson C., Laugel V., Echaniz-Laguna A., Mandel J.L., Nishino I., Laporte J.

Acta Neuropathol 2011; 121(2):253-66

Genetic inactivation of prokineticin receptor-1 leads to heart and kidney disorders

Boulberdaa M., Turkeri G., Urayama K., Dormishian M., Szatkowski C., Zimmer L., Messaddeq N., Laugel V., Dolle P., Nebigil C.G.

Arterioscler Thromb Vasc Biol 2011; 31(4):842-50

In vivo osseointegration of nano-designed composite coatings on titanium implants.

Facca S, Lahiri D, Fioretti F, Messadeq N, Mainard D, Benkirane-Jessel N, Agarwal A.

ACS Nano 2011; 5(6):4790-9

Mammalian retinal horizontal cells are unconventional GABAergic neurons

Deniz S., Wersinger E., Schwab Y., Mura C., Erdelyi F., Szabo G., Rendon A., Sahel J.A., Picaud S., Roux M.J.

J Neurochem 2011; 116(3):350-362

Microencapsulation of nanoemulsions: novel Trojan particles for bioactive lipid molecule delivery

Li X., Anton N., Ta T.M., Zhao M., Messaddeq N., Vandamme T.F.

Int J Nanomedicine 2011; 6():1313-25

Misregulated alternative splicing of BIN1 is associated with T tubule alterations and muscle weakness in myotonic dystrophy

Fugier C., Klein A.F., Hammer C., Vassilopoulos S., Ivarsson Y., Toussaint A., Tosch V., Vignaud A., Ferry A., Messaddeq N., Kokunai Y., Tsuburaya R., de la Grange P., Dembele D., Francois V., Precigout G., Boulade-Ladame C., Hummel M.C., de Munain A.L., Sergeant N., Laquerriere A., Thibault C., Deryckere F., Auboeuf D., Garcia L., Zimmermann P., Udd B., Schoser B., Takahashi M.P., Nishino I., Bassez G., Laporte J., Furling D., Charlet-Berguerand N.

Nat Med 2011; 17(6):720-5

Overproduction of Delta-Endotoxins by Sporeless Bacillus thuringiensis Mutants Obtained by Nitrous Acid Mutagenesis

Ben Khedher S., Zouari N., Messaddeq N., Schultz P., Jaoua S.

Curr Microbiol 2011; 62(1):38-43

Reevaluation of dystrophin localization in the mouse retina.

Wersinger E(1), Bordais A, Schwab Y, Sene A, Bénard R, Alunni V, Sahel JA, Rendon A, Roux MJ.

Invest Ophthalmol Vis Sci 2011; 52(11):7901-8

Stabilization of HIV-1 envelope in the CD4-bound conformation through specific cross-linking of a CD4 mimetic.

Martin G, Burke B, Thaï R, Dey AK, Combes O, Ramos OH, Heyd B, Geonnotti AR, Montefiori DC, Kan E, Lian Y, Sun Y, Abache T, Ulmer JB, Madaoui H, Guérois R, Barnett SW, Srivastava IK, Kessler P, Martin L.

J Biol Chem 2011; 286(24):21706-16

The podocyte protein nephrin is required for cardiac vessel formation

Wagner N., Morrison H., Pagnotta S., Michiels J.F., Schwab Y., Tryggvason K., Schedl A., Wagner K.D.

Hum Mol Genet 2011; 20(11):2182-94

A precise and rapid mapping protocol for correlative light and electron microscopy of small invertebrate organisms

Kolotuev I., Schwab Y., Labouesse M.

Biol Cell 2010; 102(2):121-32

Divergent roles of prokineticin receptors in the endothelial cells: angiogenesis and fenestration

Guilini C., Urayama K., Turkeri G., Dedeoglu D.B., Kurose H., Messaddeq N., Nebigil C.G.

Am J Physiol Heart Circ Physiol 2010; 298(3):H844-52

From dynamic live cell imaging to 3D ultrastructure: novel integrated methods for high pressure freezing and correlative light-electron microscopy.

Spiegelhalter C, Tosch V, Hentsch D, Koch M, Kessler P, Schwab Y, Laporte J.

PLoS One 2010; 5(2):e9014

Live-Cell One- and Two-Photon Uncaging of a Far-Red Emitting Acridinone Fluorophore

Warther D., Bolze F., Leonard J., Gug S., Specht A., Puliti D., Sun X.H., Kessler P., Lutz Y., Vonesch J.L., Winsor B., Nicoud J.F., Goeldner M.

J Am Chem Soc 2010; 132(8):2585-2590

Vinexinbeta, an atypical "sensor" of retinoic acid receptor gamma signaling: union and sequestration, separation, and phosphorylation

Lalevee S., Bour G., Quinternet M., Samarut E., Kessler P., Vitorino M., Bruck N., Delsuc M.A., Vonesch J.L., Kieffer B., Rochette-Egly C.

FASEB J 2010; 24(11):4523-34

Activating Fgfr3 Y367C mutation causes hearing loss and inner ear defect in a mouse model of chondrodysplasia

Pannier S., Couloigner V., Messaddeq N., Elmaleh-Berges M., Munnich A., Romand R., Legeai-Mallet L.

Biochim Biophys Acta 2009; 1792(2):140-7

Differential between protein and mRNA expression of CCR7 and SSTR5 receptors in Crohn's disease patients.

Taquet N, Dumont S, Vonesch JL, Hentsch D, Reimund JM, Muller CD.

Mediators Inflamm 2009; 2009():285812

Disruption of the Interaction between Transcriptional Intermediary Factor 1{beta} and Heterochromatin Protein 1 Leads to a Switch from DNA Hyper- to Hypomethylation and H3K9 to H3K27 Trimethylation on the MEST Promoter Correlating with Gene Reactivation

Riclet R., Chendeb M., Vonesch J.L., Koczan D., Thiesen H.J., Losson R., Cammas F.

Mol Biol Cell 2009; 20(1):296-305

Microcirculatory alterations in cardiac surgery: effects of cardiopulmonary bypass and anesthesia.

De Backer D, Dubois MJ, Schmartz D, Koch M, Ducart A, Barvais L, Vincent JL.

Ann Thorac Surg 2009; 88(5):1396-403

The entire zebrafish blastula-gastrula margin acts as an organizer dependent on the ratio of Nodal to BMP activity

Fauny J.D., Thisse B., Thisse C.

Development 2009; 136(22):3811-9

Transgenic myocardial overexpression of prokineticin receptor-2 (GPR73b) induces hypertrophy and capillary vessel leakage

Urayama K., Dedeoglu D.B., Guilini C., Frantz S., Ertl G., Messaddeq N., Nebigil C.G.

Cardiovasc Res 2009; 81(1):28-37

AAV-mediated intramuscular delivery of myotubularin corrects the myotubular myopathy phenotype in targeted murine muscle and suggests a function in plasma membrane homeostasis

Buj-Bello A., Fougerousse F., Schwab Y., Messaddeq N., Spehner D., Pierson C.R., Durand M., Kretz C., Danos O., Douar A.M., Beggs A.H., Schultz P., Montus M., Denefle P., Mandel J.L.

Hum Mol Genet 2008; 17(14):2132-43

A Caenorhabditis elegans model for epithelial-neuronal transdifferentiation

Jarriault S., Schwab Y., Greenwald I.

Proc Natl Acad Sci U S A 2008; 105(10):3790-5

DYC-1, a Protein Functionally Linked to Dystrophin in Caenorhabditis elegans Is Associated with the Dense Body, Where It Interacts with the Muscle LIM Domain Protein ZYX-1

Lecroisey C., Martin E., Mariol M.C., Granger L., Schwab Y., Labouesse M., Segalat L., Gieseler K.

Mol Biol Cell 2008; 19(3):785-96

Endogenous modulators of synaptic transmission: cannabinoid regulation in the supraoptic nucleus.

McDonald NA, Kuzmiski JB, Naderi N, Schwab Y, Pittman QJ.

Prog Brain Res 2008; 170():129-36

Fast 4D Microscopy

De Mey J.R., Kessler P., Dompierre J., Cordelieres F.P., Dieterlen A., Vonesch J.L., Sibarita J.B.

Methods Cell Biol 2008; 85():83-112

Liver receptor homolog 1 is essential for ovulation

Duggavathi R., Volle D.H., Mataki C., Antal M.C., Messaddeq N., Auwerx J., Murphy B.D., Schoonjans K.

Genes Dev 2008; 22(14):1871-6

Prokineticin receptor-1 induces neovascularization and epicardial-derived progenitor cell differentiation

Urayama K., Guilini C., Turkeri G., Takir S., Kurose H., Messaddeq N., Dierich A., Nebigil C.G.

Arterioscler Thromb Vasc Biol 2008; 28(5):841-9

Route of uptake of palmitoylated encephalitogenic peptides of myelin proteolipid protein by antigen-presenting cells: importance of the type of bond between lipid chain and peptide and relevance to autoimmunity

Pfender N.A., Grosch S., Roussel G., Koch M., Trifilieff E., Greer J.M.

J Immunol 2008; 180(3):1398-404

Specific properties of a C-terminal truncated androgen receptor detected in hormone refractory prostate cancer.

Lapouge G, Marcias G, Erdmann E, Kessler P, Cruchant M, Serra S, Bergerat JP, Céraline J.

Adv Exp Med Biol 2008; 617():529-34

Transfection ability and intracellular DNA pathway of nanostructured gene-delivery systems

Zhang X., Sharma K.K., Boeglin M., Ogier J., Mainard D., Voegel J.C., Mely Y., Benkirane-Jessel N.

Nano Lett 2008; 8(8):2432-6

A splicing variant of the androgen receptor detected in a metastatic prostate cancer exhibits exclusively cytoplasmic actions

Jagla M., Feve M., Kessler P., Lapouge G., Erdmann E., Serra S., Bergerat J.P., Ceraline J.

Endocrinology 2007; 148(9):4334-43

Early development of the lower deciduous dentition and oral vestibule in human embryos

Hovorakova M., Lesot H., Vonesch J.L., Peterka M., Peterkova R.

Eur J Oral Sci 2007; 115(4):280-7

Gain of affinity point mutation in the serotonin receptor gene 5-HT(2Dro) accelerates germband extension movements during Drosophila gastrulation

Schaerlinger B., Launay J.M., Vonesch J.L., Maroteaux L.

Dev Dyn 2007; 236(4):991-999

Microvascular response to red blood cell transfusion in patients with severe sepsis.

Sakr Y, Chierego M, Piagnerelli M, Verdant C, Dubois MJ, Koch M, Creteur J, Gullo A, Vincent JL, De Backer D.

Crit Care Med 2007; 35(7):1639-44

Quantitative ultrasonic tissue characterization as a new tool for continuous monitoring of chronic liver remodelling in mice

Guimond A., Teletin M., Garo E., D'Sa A., Selloum M., Champy M.F., Vonesch J.L., Monassier L.

Liver Int 2007; 27(6):854-64

The prokineticin receptor-1 (GPR73) promotes cardiomyocyte survival and angiogenesis

Urayama K., Guilini C., Messaddeq N., Hu K., Steenman M., Kurose H., Ert G., Nebigil C.G.

Faseb J 2007; 21(11):2980-2993

Unexpected paracrine action of prostate cancer cells harboring a new class of androgen receptor mutation-A new paradigm for cooperation among prostate tumor cells

Lapouge G., Erdmann E., Marcias G., Jagla M., Monge A., Kessler P., Serra S., Lang H., Jacqmin D., Bergerat J.P., Ceraline J.

Int J Cancer 2007; 121(6):1238-44

Vascular wall-produced prostaglandin E2 exacerbates arterial thrombosis and atherothrombosis through platelet EP3 receptors

Gross S., Tilly P., Hentsch D., Vonesch J.L., Fabre J.E.

J Exp Med 2007; 204(2):311-20

Assessment of thoracic epidural analgesia during general anesthesia using pupillary reflex dilation: a preliminary study.

Huybrechts I, Barvais L, Ducart A, Engelman E, Schmartz D, Koch M.

J Cardiothorac Vasc Anesth 2006; 20(5):664-7

Bile acids induce energy expenditure by promoting intracellular thyroid hormone activation

Watanabe M., Houten S.M., Mataki C., Christoffolete M.A., Kim B.W., Sato H., Messaddeq N., Harney J.W., Ezaki O., Kodama T., Schoonjans K., Bianco A.C., Auwerx J.

Nature 2006; 439(7075):484-9

Effects of drotrecogin alfa activated on microcirculatory alterations in patients with severe sepsis.

De Backer D, Verdant C, Chierego M, Koch M, Gullo A, Vincent JL.

Crit Care Med 2006; 34(7):1918-24

Incorrect shunt placement due to anatomic variations of the aortic arch during carotid endarterectomy: a rare cause of perioperative ischemia?

Koch M, Cristiani M, Schmartz D.

Anesth Analg 2006; 103(6):1617-8

Photocrosslinking/label transfer: A key step in mapping short alpha-neurotoxin binding site on nicotinic acetylcholine receptor.

Kessler P, Thai R, Beau F, Tarride JL, Ménez A.

Bioconjug Chem 2006; 17(6):1482-91

Sublingual capnometry tracks microcirculatory changes in septic patients.

Creteur J, De Backer D, Sakr Y, Koch M, Vincent JL.

Intensive Care Med 2006; 32(4):516-23

The effects of dobutamine on microcirculatory alterations in patients with septic shock are independent of its systemic effects.

De Backer D, Creteur J, Dubois MJ, Sakr Y, Koch M, Verdant C, Vincent JL.

Crit Care Med 2006; 34(2):403-8

The glutamate transporter EAAT5 works as a presynaptic receptor in mouse rod bipolar cells

Wersinger E., Schwab Y., Sahel J.A., Rendon A., Pow D.V., Picaud S., Roux M.J.

J Physiol 2006; 577(Pt 1):221-34

The V0-ATPase mediates apical secretion of exosomes containing Hedgehog-related proteins in Caenorhabditis elegans

Liegeois S., Benedetto A., Garnier J.M., Schwab Y., Labouesse M.

J Cell Biol 2006; 173(6):949-61

Binding of human papillomavirus 16 E6 to p53 and E6AP is impaired by monoclonal antibodies directed against the second zinc-binding domain of E6.

Lagrange M(1), Charbonnier S, Orfanoudakis G, Robinson P, Zanier K, Masson M, Lutz Y, Travé G, Weiss E, Deryckere F.

J Gen Virol 2005; 86(pt 4):1001-1007

Origin and developmental fate of vestigial tooth primordia in the upper diastema of the field vole (Microtus agrestis, Rodentia)

Witter K., Lesot H., Peterka M., Vonesch J.L., Misek I., Peterkova R.

Arch Oral Biol 2005; 50(4):401-9

PARP-1 and PARP-2 interact with nucleophosmin/B23 and accumulate in transcriptionally active nucleoli

Meder V.S., Boeglin M., de Murcia G., Schreiber V.

J Cell Sci 2005; 118(Pt 1):211-222

Physiological maturation of photoreceptors depends on the voltage-gated sodium channel NaV1.6 (Scn8a).

Côté PD, De Repentigny Y, Coupland SG, Schwab Y, Roux MJ, Levinson SR, Kothary R.

J Neurosci 2005; 25(20):5046-50

Purkinje-cell degeneration in prion protein-deficient mice is associated with a cerebellum-specific Doppel protein species signature.

Al Bersaoui R, Robert I, Lutz Y, Blanc F, Sommermeyer-Leroux G, Shibaguchi H, Aunis D, Fuchs JP.

FEBS Lett 2005; 579(12):2715-21

Retinoid X receptor ablation in adult mouse keratinocytes generates an atopic dermatitis triggered by thymic stromal lymphopoietin.

Li M, Messaddeq N, Teletin M, Pasquali JL, Metzger D, Chambon P.

Proc Natl Acad Sci U S A 2005; 102(41):14795-800

Dendritically released transmitters cooperate via autocrine and retrograde actions to inhibit afferent excitation in rat brain.

Hirasawa M, Schwab Y, Natah S, Hillard CJ, Mackie K, Sharkey KA, Pittman QJ.

J Physiol 2004; 559(pt 2):611-624

Expression of tetrodotoxin-sensitive and resistant sodium channels by rat melanotrophs

Schwab Y., Jahke R., Jover E.

Neuroreport 2004; 15(7):1219-23

Lactic acidosis: an early marker of propofol infusion syndrome?

Koch M, De Backer D, Vincent JL.

Intensive Care Med 2004; 30(3):522

Preparation, isolation and characterization of stage-specific spermatogenic cells for cellular and molecular analysis

Kotaja N., Kimmins S., Brancorsini S., Hentsch D., Vonesch J.L., Davidson I., Parvinen M., Sassone-Corsi P.

Nat Methods 2004; 1(3):249-54

Propofol may be safely administered by trained nonanesthesiologists. Con: Propofol: far from harmless.

Koch ME, Gevirtz C.

Am J Gastroenterol 2004; 99(7):1208-11

Acute barium intoxication and hemodiafiltration.

Koch M, Appoloni O, Haufroid V, Vincent JL, Lheureux P.

J Toxicol Clin Toxicol 2003; 41(4):363-7

A cysteine-linkable, short cleavable photoprobe with dual functionality to explore protein-protein interfaces.

Teixeira-Clerc F, Michalet S, Ménez A, Kessler P.

Bioconjug Chem 2003; 14(3):554-62

Office-based anesthesia: an overview.

Koch ME, Dayan S, Barinholtz D.

Anesthesiol Clin North America 2003; 21(2):417-43

PARP-3 localizes preferentially to the daughter centriole and interferes with the G1/S cell cycle progression

Augustin A., Spenlehauer C., Dumond H., Menissier-De Murcia J., Piel M., Schmit A.C., Apiou F., Vonesch J.L., Kock M., Bornens M., De Murcia G.

J Cell Sci 2003; 116(Pt 8):1551-1562

Preferential nuclear localization of the human papillomavirus type 16 E6 oncoprotein in cervical carcinoma cells.

Masson M(1), Hindelang C, Sibler AP, Schwalbach G, Travé G, Weiss E.

J Gen Virol 2003; 84(pt 8):2099-2104

Serotonin is a novel survival factor of cardiomyocytes: mitochondria as a target of 5-HT2B receptor signaling

Nebigil C.G., Etienne N., Messaddeq N., Maroteaux L.

Faseb J 2003; 17(10):1373-5

The molecular nature of the zebrafish tail organizer

Agathon A., Thisse C., Thisse B.

Nature 2003; 424(6947):448-52

Tooth morphogenesis and pattern of odontoblast differentiation

Lisi S., Peterkova R., Peterka M., Vonesch J.L., Ruch J.V., Lesot H.

Connect Tissue Res 2003; 44 Suppl 1():167-70

Acetylcholinesterase is required for neuronal and muscular development in the zebrafish embryo

Behra M., Cousin X., Bertrand C., Vonesch J.L., Biellmann D., Chatonnet A., Strahle U.

Nat Neurosci 2002; 5(2):111-118.

Asymmetrical morphogenesis and medio-lateral positioning of molars during mouse development

Cam Y., Fausser J.L., Vonesch J.L., Peterkova R., Peterka M., Halaskova M., Lesot H.

Eur J Oral Sci 2002; 110(1):35-43

Cell differentiation induces TIF1beta association with centromeric heterochromatin via an HP1 interaction

Cammas F., Oulad-Abdelghani M., Vonesch J.L., Huss-Garcia Y., Chambon P., Losson R.

J Cell Sci 2002; 115(Pt 17):3439-48.

CSB is a component of RNA pol I transcription

Bradsher J., Auriol J., Proietti de Santis L., Iben S., Vonesch J.L., Grummt I., Egly J.M.

Mol Cell 2002; 10(4):819-29

Expression of the human &mgr; opioid receptor in a stable Sf9 cell line

Kempf J., Snook L.A., Vonesch J.L., Dahms T.E., Pattus F., Massotte D.

J Biotechnol 2002; 95(2):181-187.

How do short neurotoxins bind to a muscular-type nicotinic acetylcholine receptor?

Teixeira-Clerc F, Ménez A, Kessler P.

J Biol Chem 2002; 277(28):25741-7

Sef is a feedback-induced antagonist of Ras/MAPK-mediated FGF signalling

Furthauer M., Lin W., Ang S.L., Thisse B., Thisse C.

Nat Cell Biol 2002; 4(2):170-4.

The PtdIns3P phosphatase myotubularin is a cytoplasmic protein that also localizes to Rac1-inducible plasma membrane ruffles

Laporte J., Blondeau F., Gansmuller A., Lutz Y., Vonesch J.L., Mandel J.L.

J Cell Sci 2002; 115(Pt 15):3105-17.

The retinoic acid receptors RARalpha and RARgamma are required for inner ear development

Romand R., Hashino E., Dolle P., Vonesch J.L., Chambon P., Ghyselinck N.B.

Mech Dev 2002; 119(2):213-23.

Ablation of serotonin 5-HT(2B) receptors in mice leads to abnormal cardiac structure and function

Nebigil C.G., Hickel P., Messaddeq N., Vonesch J.L., Douchet M.P., Monassier L., Gyorgy K., Matz R., Andriantsitohaina R., Manivet P., Launay J.M., Maroteaux L.

Circulation 2001; 103(24):2973-9.

Assembly of C. elegans apical junctions involves positioning and compaction by LET-413 and protein aggregation by the MAGUK protein DLG- 1

McMahon L., Legouis R., Vonesch J.L., Labouesse M.

J Cell Sci 2001; 114(Pt 12):2265-77.

Calcium-dependent translocation of synaptotagmin to the plasma membrane in the dendrites of developing neurones.

Schwab Y, Mouton J, Chasserot-Golaz S, Marty I, Maulet Y, Jover E.

Brain Res Mol Brain Res 2001; 96(1-2):1-13

casanova encodes a novel Sox-related protein necessary and sufficient for early endoderm formation in zebrafish

Kikuchi Y., Agathon A., Alexander J., Thisse C., Waldron S., Yelon D., Thisse B., Stainier D.Y.

Genes Dev 2001; 15(12):1493-505.

Crown morphology and pattern of odontoblast differentiation in lower molars of tabby mice

Lisi S., Peterkova R., Kristenova P., Vonesch J.L., Peterka M., Lesot H.

J Dent Res 2001; 80(11):1980-3.

Retinoic acid rescues inner ear defects in Hoxa1 deficient mice

Pasqualetti M., Neun R., Davenne M., Rijli F.M.

Nat Genet 2001; 29(1):34-9.

Inhibition of apoptosis in the primary enamel knot does not affect specific tooth crown morphogenesis in the mouse

Coin R., Kieffer S., Lesot H., Vonesch J.L., Ruch J.V.

Int J Dev Biol 2000; 44(4):389-96

Negative cross-talk between p53 and the glucocorticoid receptor and its role in neuroblastoma cells

Sengupta S., Vonesch J.L., Waltzinger C., Zheng H., Wasylyk B.

Embo J 2000; 19(22):6051-6064

Position and growth of upper and lower tooth primordia in prenatal mouse--3D study

Peterka M., Vonesch J.L., Ruch J.V., Cam Y., Peterkova R., Lesot H.

J Craniofac Genet Dev Biol 2000; 20(1):35-43

Regeneration of halved embryonic lower first mouse molars: correlation with the distribution pattern of non dividing IDE cells, the putative organizers of morphogenetic units, the cusps

Coin R., Schmitt R., Lesot H., Vonesch J.L., Ruch J.V.

Int J Dev Biol 2000; 44(3):289-95

Serotonin 2B receptor is required for heart development

Nebigil C.G., Choi D.S., Dierich A., Hickel P., Le Meur M., Messaddeq N., Launay J.M., Maroteaux L.

Proc Natl Acad Sci U S A 2000; 97(17):9508-13

The presence of rudimentary odontogenic structures in the mouse embryonic mandible requires reinterpretation of developmental control of first lower molar histomorphogenesis

Viriot L., Lesot H., Vonesch J.L., Ruch J.V., Peterka M., Peterkova R.

Int J Dev Biol 2000; 44(2):233-40

Alterations in the incisor development in the Tabby mouse

Miard S., Peterkova R., Vonesch J.L., Peterka M., Ruch J.V., Lesot H.

Int J Dev Biol 1999; 43(6):517-29

Aspects of cell proliferation kinetics of the inner dental epithelium during mouse molar and incisor morphogenesis: a reappraisal of the role of the enamel knot area

Coin R., Lesot H., Vonesch J.L., Haikel Y., Ruch J.V.

Int J Dev Biol 1999; 43(3):261-7

Gliogenesis depends on glide/gcm through asymmetric division of neuroglioblasts

Bernardoni R., Kammerer M., Vonesch J.L., Giangrande A.

Dev Biol 1999; 216(1):265-75

Initial features of the inner dental epithelium histo-morphogenesis in the first lower molar in mouse

Lesot H., Peterkova R., Schmitt R., Meyer J.M., Viriot L., Vonesch J.L., Senger B., Peterka M., Ruch J.V.

Int J Dev Biol 1999; 43(3):245-54

Morphogenesis of the lower incisor in the mouse from the bud to early bell stage

Kieffer S., Peterkova R., Vonesch J.L., Ruch J.V., Peterka M., Lesot H.

Int J Dev Biol 1999; 43(6):531-9

Mouse odontogenesis in vitro: the cap-stage mesenchyme controls individual molar crown morphogenesis

Schmitt R., Lesot H., Vonesch J.L., Ruch J.V.

Int J Dev Biol 1999; 43(3):255-60

Plasticity within the lateral somatic mesoderm of Drosophila embryos

Jagla T., Bellard F., Vonesch J.L., Bellard M., Dastugue B., Jagla K.

Int J Dev Biol 1999; 43(6):571-3

Serotonin synchronises convergent extension of ectoderm with morphogenetic gastrulation movements in Drosophila

Colas J., Launay J., Vonesch J., Hickel P., Maroteaux L.

Mech Dev 1999; 87(1-2):77-91

The putative nuclear receptor mediator TIF1(&agr;) is tightly associated with euchromatin

Remboutsika E., Lutz Y., Gansmuller A., Vonesch J.L., Losson R., Chambon P.

Journal of Cell Sciences 1999; 112():1671-1683

Activity of the delta-opioid receptor is partially reduced, whereas activity of the kappa-receptor is maintained in mice lacking the mu- receptor

Matthes H.W.D., Smadja C., Valverde O., Vonesch J.L., Foutz A.S., Boudinot E., Denavit-Saubie M., Severini C., Negri L., Roques B.P., Maldonado R., Kieffer B.L.

J.Neurosci. 1998; 18(18):7285-7295

Early stages of tooth morphogenesis in mouse analyzed by 3D reconstructions

Lesot H., Peterkova R., Viriot L., Vonesch J.L., Tureckova J., Peterka M., Ruch J.V.

Eur.J.Oral.Sci. 1998; Vol 106():64-70

Functional association of poly(ADP-ribose) polymerase with DNA polymerase alpha-primase complex: a link between DNA strand break detection and DNA replication

Dantzer F., Nasheuer H.P., Vonesch J.L., de Murcia G., Ménissier-de Murcia J.

Nucleic Acids Res. 1998; 26():1891-1898

Lasp-1, a novel type of actin-binding protein accumulating in cell membrane extensions

Schreiber V.R., Moog-Lutz C., Regnier C.H., Chenard M.P., Boeuf H., Vonesch J.L., Tomasetto C., Rio M.C.

Mol.Med. 1998; Vol 4, Iss 10():675-687

Two distinct nuclear receptor interaction domains in NSD1, a novel SET protein that exhibits characteristics of both corepressors and coactivators

Huang N.W., vom Baur E., Garnier J.M., Lerouge T., Vonesch J.L., Lutz Y., Chambon P., Losson R.

EMBO J. 1998; Vol 17, Iss 12():3398-3412

3-D reconstructions for graphical databases of gene expression

Baldock R.A., Verbeek F.J., Vonesch J.L.

Semin.Cell & Develop.Biol. 1997; 8():499-507

5-HT2B receptor-mediated serotonin morphogenetic functions in mouse cranial neural crest and myocardiac cells

Choi D.S., Ward S.J., Messaddeq N., Launay J.M., Maroteaux L.

Development 1997; Vol 124, Iss 9():1745-1755

Mouse molar morphogenesis revisited by three-dimensional reconstruction. III. Spatial distribution of mitoses and apoptoses up to bell-staged first lower molar teeth

Viriot L., Peterkova R., Vonesch J.L., Peterka M., Ruch J.V., Lesot H.

Int.J.Dev.Biol. 1997; 41():679-690

Spatio-temporally controlled site-specific somatic mutagenesis in the mouse

Brocard J., Warot X., Wendling O., Messaddeq N., Vonesch J.L., Chambon P., Metzger D.

Proc.Natl.Acad.Sci.U.S.A. 1997; Vol 94, Iss 26():14559-14563

Target-dependent synaptogenesis: Inductive effect of pituitary melanotrophs on their central innervation

Egles C., Schimchowitsch S., Vonesch J.L., Rene F., Felix J.M., Stoeckel M.E.

Synapse. 1997; Vol 27, Iss 4():267-277

Apoptosis is involved in the disappearance of the diastemal dental primordia in mouse embryo

Tureckova J., Lesot H., Vonesch J.L., Peterka M., Peterkova R., Ruch J.V.

Int.J.Dev.Biol. 1996; Vol 40, Iss 2():483-489

Glide directs glial fate commitment and cell fate switch between neurones and glia

Vincent S., Vonesch J.L., Giangrande A.

Development 1996; 122():131-139

Mouse molar morphogenesis revisited by three dimensional reconstruction. I. Analysis of initial stages of the first upper molar development revealed two transient buds.

Peterkova R., Lesot H., Vonesch J.L., Peterka M., Ruch J.V.

Int.J.Dev.Biol. 1996; Vol 40, Iss 5():1009-1016

Roles of retinoic acid receptors and of Hox genes in the patterning of the teeth and of the jaw skeleton

Mark M., Lohnes D., Mendelsohn C., Dupe V., Vonesch J.L., Kastner P., Rijli F., Bloch-Zupan A., Chambon P.

Int.J.Dev.Biol. 1995; 39():111-121

The influence of positive selection on RAG expression in thymocytes

Kouskoff V., Vonesch J.L., Benoist C., Mathis D.

Eur.J.Immunol. 1995; 25():54-58

Genetic analysis of RXR alpha developmental function: convergence of RXR and RAR signaling pathways in heart and eye morphogenesis

Kastner P., Grondona J.M., Mark M., Gansmuller A., Le Meur M., Decimo D., Vonesch J.L., Dolle P., Chambon P.

Cell 1994; 78():987-1003

Stage and tissue-specific expression of the alcohol dehydrogenase 1 (Adh-1) gene during mouse development

Vonesch J.L., Nakshatri H., Philippe M., Chambon P., Dolle P.

Dev.Dyn. 1994; 199():199-213

Two rhombomeres are altered in Hoxa-1 mutant mice

Mark M., Lufkin T., Vonesch J.L., Ruberte E., Olivo J.C., Dolle P., Gorry P., Lumsden A., Chambon P.

Development 1993; 119():319-338